This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 956314.
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Prof. Jean-Pierre Changeux presentation at the Janeiro-na-Madeira Winter Summer School 202529/1/2025 Check the talk of Prof. Jean-Pierre Changeux (Institut Pasteur, France) exploring the evolution of allosteric regulation, from its historical foundations to cutting-edge perspectives at the atomic level. Presented at the Janeiro-na-Madeira Winter Summer School 2025, a satellite event of ALLODD, this lecture delves into the molecular mechanisms of allostery and its impact on drug discovery.
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Title: Integrating Simulation Methods into Drug Discovery Workflows: Successes, Gaps and Opportunities
Lecturer: Ian Wall, GSK Date: 12 February, 2025, 15:00 - 16:30 (CET) Venue: online Title: Emerging Strategies in Peptide Drug Discovery
SPEAKERS:
Date: March 4, 2025, 16:30 - 18:30 (CET) Venue: online Check the new ALLODD publication:
Cardona, A., Ivanova, V., Beltrán-Debón, R., Barril, X., Castillón, S., Díaz, Y. and Matheu, M.I., 2025 Syntheses of differentially fluorinated triazole-based 1-deoxysphingosine analogues en route to SphK inhibitors. Org. Biomol. Chem. https://doi.org/10.1039/D4OB01656D Check the new ALLODD publication:
Bemelmans, M.P., Cournia, Z., Damm-Ganamet, K.L., Gervasio, F.L., Pande, V., 2025 Computational advances in discovering cryptic pockets for drug discovery. Curr. Opin. Struct. Biol. https://doi.org/10.1016/j.sbi.2024.102975 Check the new ALLODD publication:
Fournier, L., Arras, P., Pekar, L., Kolmar, H., Zielonka, S., Toleikis, L., Becker, S., 2025 Enhancing NK-cell mediated tumor killing of B7-H6 positive cells with bispecific antibodies targeting allosteric sites of NKp30. Molecular Therapy Oncology. https://doi.org/10.1016/j.omton.2024.200917 |
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