Dr. György Ferenczy
Host Organization Research Center for Natural Sciences, Hungary Medicinal Chemistry Research Group Keserű Lab ALLODD Role Co-Supervisor for ESR7 |
Brief Bio György G. Ferenczy is a senior research fellow at the Research Centre for Natural Sciences and at the Semmelweis University. He obtained a PhD in computational chemistry from the Eötvös University of Budapest and was postdoc at the University of Oxford and at the University of Nancy. Later he worked as a computational chemist at Gedeon Richter and Sanofi. His research interest includes the development and application of computational tools for extended biochemical systems with special focus on drug discovery. Selected Publications Mihalovits LM, Ferenczy GG, Keserű GM Mechanistic and thermodynamic characterization of oxathiazolones as potent and selective covalent immunoproteasome inhibitors Comput Struct Biotechnol J. 2021, 19:4486-4496 https://doi.org/10.1016/j.csbj.2021.08.008 Kollár L, Gobec M, Szilágyi B, Proj M, Knez D, Ábrányi-Balogh P, Petri L, Imre T, Bajusz D, Ferenczy GG, Gobec S, Keserű GM, Sosič I Discovery of selective fragment-sized immunoproteasome inhibitors Eur J Med Chem. 2021, 219:113455 https://doi.org/10.1016/j.ejmech.2021.113455 Mihalovits LM, Ferenczy GG, Keserű GM Affinity and Selectivity Assessment of Covalent Inhibitors by Free Energy Calculations J Chem Inf Model. 2020, 60(12):6579-6594 https://doi.org/10.1021/acs.jcim.0c00834 Ferenczy GG, Keserű GM Thermodynamic profiling for fragment-based lead discovery and optimization Expert Opin Drug Discov. 2020, 15(1):117-129 https://doi.org/10.1080/17460441.2020.1691166 Kiss DJ, Ferenczy GG A detailed mechanism of the oxidative half-reaction of d-amino acid oxidase: another route for flavin oxidation Org Biomol Chem. 2019, 17(34):7973-7984 https://doi.org/10.1039/c9ob00975b |
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This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 956314.
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