Dr. Roman Zubarev
Karolinska Institutet, Sweeden
Department of Medical Biochemistry and Biophysics
Main Supervisor for ESR9
Roman Zubarev is professor of Medicinal Proteomics at the Karolinska Institutet, Stockholm, Sweden. He has received a B.S. and M.Sc. degree from the Moscow Engineering Physics Institute, Russia and Ph.D. degree in Analytical Chemistry from the Uppsala University, Sweden. His research is dealing with the development of instruments and methods for mass spectrometry based proteomics and their applications to diverse biomedical problems. Among these are the mechanism, biomarkers and potential preventive treatments of Alzheimer’s disease, the targets and action mechanisms of drugs against cancer cells and pathogenic microorganisms, and the mystery of stem cells. He has also authored and tested the “isotopic resonance” hypothesis, as well as verified cell self-assembly as a possible origin of life on Earth.
Covariation of Peptide Abundances Accurately Reflects Protein Concentration Differences.
Zhang B, Pirmoradian M, Zubarev R, Käll L
Mol. Cell Proteomics 2017 05;16(5):936-948
Self-assembly of Deinococcus radiodurans supports nanocell scenario of life origin.
Bernadotte A, Semenova V, Musial VAM, Kasprzykowska A, Zubarev RA
Discoveries 2017, Jan-Mar; 5(1):e72
Cytotoxic and Proinflammatory Effects of Metal-Based Nanoparticles on THP-1 Monocytes Characterized by Combined Proteomics Approaches.
Tarasova N, Gallud A, Ytterberg A, Chernobrovkin A, Aranzaes J, Astruc D, et al
J. Proteome Res. 2017 02;16(2):689-697
SpotLight Proteomics: uncovering the hidden blood proteome improves diagnostic power of proteomics.
Lundström S, Zhang B, Rutishauser D, Aarsland D, Zubarev R
Sci Rep 2017 02;7():41929
On the Effect of Planetary Stable Isotope Compositions on Growth and Survival of Terrestrial Organisms.
Xie X, Zubarev R
PLoS ONE 2017 ;12(1):e0169296
How well can morphology assess cell death modality? A proteomics study.
Chernobrovkin A, Zubarev R
Cell Death Discov ;2():16068
Establishing a Proteomics-Based Monocyte Assay To Assess Differential Innate Immune Activation Responses.
Tarasova N, Ytterberg A, Lundberg K, Zhang X, Harris R, Zubarev R
J. Proteome Res. 2016 07;15(7):2337-45
Isoelectric point region pI≈7.4 as a treasure island of abnormal proteoforms in blood
Pirmoradian M, Aarsland D, Zubarev RA
Discoveries 2016, Jul-Sep; 4(4):e67
DeMix-Q: Quantification-Centered Data Processing Workflow.
Zhang B, Käll L, Zubarev R
Mol. Cell Proteomics 2016 Apr;15(4):1467-78
Multijunction Capillary Isoelectric Focusing Device Combined with Online Membrane-Assisted Buffer Exchanger Enables Isoelectric Point Fractionation of Intact Human Plasma Proteins for Biomarker Discovery.
Pirmoradian M, Astorga-Wells J, Zubarev R
Anal. Chem. 2015 Dec;87(23):11840-6
This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 956314.