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ESR12: Léxane Fournier

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Host Organization
Protein Engineering & Antibody Technologies, Merck Healthcare KGaA

Supervisors
Dr. Stefan Becker
Dr. Lars Toleikis
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Identification of new targets from screening
using biochemical and cell based assays

Objectives: 
1) Development of biochemical assays to detect allosteric inhibitors from screening.
2) Retrospect analysis of available in-house targets with known allosteric inhibition mechanism.
3) Expanded the methodology to new target classes with unknown allosteric mechanism in the ALLOstery in Drug Discovery framework of the consortium for medium to high throughput screening methods.
 
Expected Results: 
1) New biochemical assay platform for the medium to high throughput detection of allosteric inhibitors.
2) Validation of known allosteric inhibitors from biochemical screening.
3) Transfer of methodology to new target classes

Brief Scientific Bio
Léxane Fournier began her studies by completing a bachelor’s degree in biochemistry at Clermont Auvergne University (Clermont-Ferrand, France). She then joined the master's program in biological engineering at Polytech Clermont, during which she performed two thesis projects. The first was carried out in collaboration with Ablynx NV (Ghent, Belgium). The second was held at Merck Healthcare KGaA (Vevey, Switzerland) and focused on cutting-edge technologies for cell line development. She also completed a master's degree in chemistry at Clermont Auvergne University. After her dual graduation, she joined the Protein Engineering and Antibody Technologies group at Merck Healthcare KGaA (Darmstadt, Germany) as an ESR as part of the ALLODD ITN project.
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This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 956314.
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  • Home
    • ALLODD Overview
    • Governing Bodies
  • People
    • Beneficiaries
    • Partner Organisations
    • Supervisors
    • Early Stage Researchers
  • Research
    • Work Packages
    • Individual Research Projects
  • Training
    • Training Events >
      • 1st Workshop and PhD Induction Course
      • 1st Training School & Networking Meeting
      • Allostery in Drug Discovery Awareness Event and Symposium
      • 2nd Training School & Networking Meeting
      • IPR Training for Researchers & ESR Presentations on the Progress of their Research
      • 3rd Training School & Networking Meeting
      • European Conference in Allostery in Drug Discovery >
        • Abstract submission
        • Registration
      • Final Networking Meeting
    • Secondments
    • ALLODD Webinars
    • Courses & Lectures
    • Journal Club
  • Dissemination
    • Publications
    • Dissemination Events
    • Science Slams
    • Communication Material
    • Social Media
    • Newsletter
  • Events
    • ALLODD Events
    • Satellite Events
  • Newsroom
    • Press releases
  • Job Openings
  • Blog
  • Contact